For kde centric, my first recommendation to you would be pclinuxos when it goes final. I usually hate rpm-based distros, but this is the most capable and friendly kde based distro. Very very simple to use and everything just works.
Kubuntu is nice, but just plain and not as bleeding edge.
SUse is not easily workable. It is a chore to manage and it is slower or bloated.
Fedora 6 was believed to be fast as well for kde.
Mepis is one of the best kde centric distros.
Sabayon is awesome, but the gentoo heritage may make it slightly challenging to manage. It is beautiful and fast once installed though.
VectorSoho is very fast. Alas only at xorg 6.9 so far. Still waiting. This has been fast for me in the past. I need Beryl though.
I did not like Mandrake or Suse. Fedora was seemingly beautiful to me and tempting look-wise, pclinuxos is to me the best put together rpm-based distro of the bunch. I may be wrong. For power users, partial to only rpm-based distro, Fedora 6 is the best option.
I prefer slack-based distros {Zenwalk}, then Debian-based ones {Ubuntu, Mepis, Sidux}, Sabayon, and pclinuxos.
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