I agree with ra7411 and use audacious for audio; for video I am in agreement with mIk3_08 and choose vlc.
Both these applications are relatively simple but work well with playlists and as far as I am concerned do all I need without too many GUI bells and whistles. They can play any file I have thrown at them which is what matters to me.
It's the music or video I want, not some fancy GUI application.
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