I had the similar problem with the Canon Pixma MG5450 (MG5400 series) using Ubuntu 15.10.
Problem:
Using "Simple Scan" to scan a document failed with:
Failed to scan
Unable to connect to scanner
But the device was properly discovered using scanimage -L
$ scanimage -L
$ device `pixma:MG5400_C5BFDC000000' is a CANON Canon PIXMA MG5400 Series multi-function peripheral
Solution:
Download 3 packages from Debian Expirimental - Libs
libjpeg62-turbo
Version: 1:1.4.80-115-gfb907b2-1
libsane-common
Version: 1.0.26~git20151121-1
libsane
Version: 1.0.26~git20151121-1
(My reputation won't allow me to add more then 2 links. Otherwise i would have linked those libraries.)
Install *deb packages
# #Install the downloaded packages as root
# dpkg -i libjpeg62-turbo_1.4.80-115-gfb907b2-1_amd64.deb
# dpkg -i libsane-common_1.0.26~git20151121-1_all.deb
# dpkg -i libsane_1.0.26~git20151121-1_amd64.deb
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