I'm having a problem with gnome. When I press a multimedia key on my keyboard (or obstensibly other hotkeys although I haven't figured out exactly what). My left-mouse button stops responding. The right mouse button works fine and the mouse tracks fine. I can go into the mouse control panel and switch it to a left handed mouse and the left mouse button works, but not the right.

I ran 'xinput test "HP Mouse"', and I can see the left mouse clicks coming through. So X11 at least thinks it's coming through. I've got nothing interesting that I can find in /var/log.

This is really generic USB hardware. HP Mouse and Microsoft Digital Media Keyboard.

I'm really stumped as to where to continue with my troubleshooting. Any thoughts?