If you want to erase everything on your hard-drive and install Ubuntu 10.04 Lucid follow these steps:
1. Boot from the Live CD and select Install on Hard-drive
2. Select country & keyboard from screens that appear next
3. When partition screen appears select Use Entire Hard-Drive (easiest)
4. On next screen type user name, password and computer name
5. Install (grub will sort itself out from here)
Reboot and you'll have a fresh Ubuntu install...
If you are using a graphics card like nvidia or ati then you will be prompter to install a Proprietary driver in the top right of the screen, other than that you might like to check out these sites for additional software/repositories:
http://www.getdeb.net and
http://www/medibuntu.org
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