I had the same problem. The messages ((firefox-bin:22382): GLib-WARNING **: g_set_prgname() called multiple times) appear to be an unrelated symptom. Prism seems to be the issue.
Part of the apparent reason for many different proposed solutions is that once I successfully start firefox in safe mode (i.e. with -safe-mode), it restarts fine without any additional options. Once. If I stop it and try to start it again, it fails without any additional messages.
None of the above proposed cures fixed the problem in my case.
By a tedious process of alimination, I identified the trigger as prism: if I disable it, I have no problems, if I re-enable it, I bring the problem back. This extension is not particularly useful: it enables you to create prism launchers from Firefox, but you can do the same by editing XML files...
My versions: FF 3.6.2pre, prism 1.0b3 (from http://ppa.launchpad.net/ubuntu-mozi...y/ppa/ubuntu): I _really_ wanted tear-off tabs
This helped me realize just how much I depend in firefox working properly on my desktop - loads of thanks to all the Mozilla developers!
HTH



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