It looks like Desura officially launched a Linux client to the public.
I have not had a chance to try this yet, but it looks awesome. It's a Steam type distribution platform that claims to be easy to install, patch and play games on any Linux distro.

The list of games is pretty impressive. Mount & Blade, Sanctum, Fallout 1&2, Humble Bundle types and more. Has anyone been using this? Is this too good to be true? I hope this really works!