I've tried both Bibus and Zotero, and I have to say that I much prefer Zotero. It is a little while since I used Bibus, but from what I can recall, I found it a frustrating experience. I remember having problems with formatting and inserting my references, and with defining the kinds of fields I wanted for my entries. I also remember spending a long time trying to (unsuccessfully) solve those problems. But like I say, that was a while ago, and my memory is a little fuzzy on the subject.
I am very enthusiastic about Zotero. I like the way it supports tagging, notes, and attaching PDFs, etc. I like the fact that it's quite flexible in terms of how it allows you to organise your references, and I like it that I can search my references, PDFs and web-pages. I like the way I can 'suck' web pages into it, and it handles citations in OpenOffice very well.
One thing that Zotero currently lacks is a way to create customised citation and bibliographic styles (though a solution is in the pipeline for that).
I suppose the one thing that I dislike about Zotero is that it is a Firefox add-on (earlycj5 makes the same point above). Personally, I would prefer my bibliography software to be a a desktop application in its own right, rather than being a Firefox add-on. That said, I can understand why the decision was made to make it as an add-on. Implementing Zotero in this way has had a lot of benefits - it has made it cross-platform, immediately web-aware, and has given Zotero access to a lot of Firefox users. In this sense, the decision to make Zotero as an add-on was undoubtedly a good one.
One final advantage of Zotero over Bibus - I could be quite wrong here, and I don't mean any disrespect to the Bibus developers, but I never got the impression that Bibus development was moving very quickly. As such, it didn't seem like a good long term bet. Zotero, on the other hand, is moving forward rapidly, with new features coming out all the time. A major new version is scheduled to come out at the same time as Firefox 3, and should take advantage of the new bells and whistles in the browser.
Phew, I really didn't mean to write that much!
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