Wow, I used to have a Cyrix 166+ (clocked at 133Mhz) from a firm called Maple Electronics. The keyboard connection I think was called an AT connection. I used a serial mouse for a long time, when I upgraded to a Microsoft Intellimouse (with a wheel! woo) it came with a PS/2 to serial adapter which came in very handy as I quite liked the serial port. I seem to recall DSL having trouble with a serial mouse. But I ditched the PC before I properly got into Linux, and now regret it a little. In fact I was told mockingly "that's just wrong" when I recommended a serial mouse over a USB mouse for compatibility with a Windows laptop in work. Apart from appreciation for the serial port and serial mice, I can't help much, except to say I think an older version of DSL or Puppy Linux may work.
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