I nearly always change the distro name and do a safe-upgrade ...... part way through 12.04 to 12.10 ....
This time it went well and will wait now till closer to release date to do another safe-upgrade.
Few things I have noticed so far .... as the main thing I like to do using Ubuntu and its derivatives is 3d work ..... but this time wings3d has dependency problems and k3dsurf is no longer in the repos for download.
Makehuman .... will not install either as its deb calls for Python2.6 ....... although Python2.7 is installed ..... this time it seems not to want to install.
But as we know its not complete yet so things may change.