In Ubuntu 10.04, Rosetta Stone V3.3.7 works fine in Wine 1.1.44 except for the microphone!
This is a know bug in wine for a long time.
Bug 14559 - Rosetta stone v3 microphone detection
So it's not really much use.
From what I've read it seems to has something to do with pulseaudio, (I could be wrong about that).
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