In case you missed it, Frank's Corner has the 411 on getting iTunes 6 running in the new version of iTunes in the newest wine:
You'll have to compile wine, but otherwise the install was super easy.
I'll put up some details on getting things going if anyone would like. Now excellent podcasting managment and access to iTunes store! No iPod support yet, but I'm working on trying to get the things which worked to get it working in Crossover--will report back.